{"id":9253,"date":"2025-10-21T17:02:41","date_gmt":"2025-10-21T09:02:41","guid":{"rendered":"https:\/\/chimebiologics.com\/?p=9253"},"modified":"2026-03-20T14:13:49","modified_gmt":"2026-03-20T06:13:49","slug":"sunrock-biopharma-and-chime-biologics-announce-strategic-collaboration-to-advance-development-of-anti-ccr9-antibody-srb5","status":"publish","type":"post","link":"https:\/\/chimebiologics.com\/zh\/sunrock-biopharma-and-chime-biologics-announce-strategic-collaboration-to-advance-development-of-anti-ccr9-antibody-srb5\/","title":{"rendered":"SunRock Biopharma\u4e0e\u9f0e\u5eb7\u751f\u7269\u5ba3\u5e03\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u63a8\u8fdb\u6297CCR9\u6297\u4f53SRB5\u5f00\u53d1"},"content":{"rendered":"<div class='flex_column av-mcn1nejp-0182da29d964c125ba238ee717c164b6 av_one_full  avia-builder-el-0  el_before_av_two_third  avia-builder-el-first  first no_margin flex_column_div '     ><section  class='av_textblock_section av-mcn1dzio-4ecd921777f883834fd6d75acccec62f' 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Biopharma\u4e0e\u9f0e\u5eb7\u751f\u7269\u5ba3\u5e03\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u63a8\u8fdb\u6297CCR9\u6297\u4f53SRB5\u5f00\u53d1<\/strong><\/h1>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-9258 aligncenter\" src=\"https:\/\/chimebiologics.com\/wp-content\/uploads\/2025\/10\/\u5408\u4f5cbanner1.jpg\" alt=\"\" width=\"1233\" height=\"526\" srcset=\"https:\/\/chimebiologics.com\/wp-content\/uploads\/2025\/10\/\u5408\u4f5cbanner1.jpg 750w, https:\/\/chimebiologics.com\/wp-content\/uploads\/2025\/10\/\u5408\u4f5cbanner1-300x128.jpg 300w, https:\/\/chimebiologics.com\/wp-content\/uploads\/2025\/10\/\u5408\u4f5cbanner1-705x301.jpg 705w\" sizes=\"auto, (max-width: 1233px) 100vw, 1233px\" \/><\/p>\n<p><strong><b>2025\u5e7410\u670821\u65e5<\/b><\/strong><strong><b>\uff0c\u897f\u73ed\u7259\u5723\u5730\u4e9a\u54e5<\/b><\/strong><strong><b>-\u5fb7\u5b54\u6ce2\u65af\u7279\u62c9<\/b><\/strong><strong><b>\u548c<\/b><\/strong><strong><b>\u4e2d\u56fd\u6b66\u6c49<\/b><\/strong><strong><b>\u00a0\u2013 <\/b><\/strong>\u4e13\u6ce8\u4e8e\u5f00\u53d1\u65b0\u4e00\u4ee3\u6cbb\u7597\u6027\u6297\u4f53\u7684\u751f\u7269\u6280\u672f\u516c\u53f8SunRock Biopharma\u4e0e\u5168\u7403\u9886\u5148\u7684\u751f\u7269\u836fCDMO\u516c\u53f8\u9f0e\u5eb7\u751f\u7269\uff08Chime Biologics\uff09\u4eca\u65e5\u5ba3\u5e03\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u63a8\u8fdbSRB5\u7684\u5f00\u53d1\u3002SRB5\u662f\u4e00\u79cd\u65b0\u578b\u6297CCR9\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u6cbb\u7597\u708e\u75c7\u6027\u80a0\u75c5\uff08IBD\uff09\uff0c\u5e76\u6709\u671b\u62d3\u5c55\u81f3\u5176\u4ed6\u514d\u75ab\u4ecb\u5bfc\u708e\u75c7\u6027\u75be\u75c5\u3002<\/p>\n<p>SRB5\u662f\u4e00\u79cd\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u5177\u5907\u589e\u5f3a\u7684ADCC\uff08\u6297\u4f53\u4f9d\u8d56\u7ec6\u80de\u4ecb\u5bfc\u7ec6\u80de\u6bd2\u4f5c\u7528\uff09\u529f\u80fd\uff0c\u53ef\u9009\u62e9\u6027\u6e05\u9664\u53c2\u4e0e\u6162\u6027\u80a0\u9053\u708e\u75c7\u7684CCR9+\u7ec6\u80de\u3002\u8fd9\u4e00\u5019\u9009\u836f\u7269\u662fSunRock\u5728\u5176\u6297CCR9\u5e73\u53f0\u4e0a\u7684\u6700\u65b0\u6210\u679c\uff0c\u6807\u5fd7\u7740\u5728\u514b\u7f57\u6069\u75c5\u548c\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\u7b49\u75be\u75c5\u7684\u7cbe\u51c6\u6cbb\u7597\u4e0a\u8fc8\u51fa\u4e86\u91cd\u8981\u4e00\u6b65\u3002\u901a\u8fc7\u6b64\u6b21\u5408\u4f5c\uff0cSunRock Biopharma\u5c06\u501f\u52a9\u9f0e\u5eb7\u751f\u7269\u7b26\u5408\u5168\u7403\u6807\u51c6\u7684GMP\u751f\u4ea7\u5e73\u53f0\uff0c\u52a0\u901f\u63a8\u8fdbSRB5\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u4e0e\u6ce8\u518c\u7533\u62a5\u8fdb\u7a0b\u3002<\/p>\n<p><strong><b>SunRock Biopharma\u9996\u5e2d\u6267\u884c\u5b98Laureano Sim\u00f3n\u535a\u58eb<\/b><\/strong>\u8868\u793a\uff1a\u201c\u4e0e\u9f0e\u5eb7\u751f\u7269\u7684\u5408\u4f5c\u662f\u6211\u4eec\u2018\u5728\u5404\u4e2a\u7814\u53d1\u9636\u6bb5\u643a\u624b\u4e16\u754c\u7ea7\u4f19\u4f34\u2019\u6218\u7565\u7684\u91cd\u8981\u91cc\u7a0b\u7891\u3002\u9f0e\u5eb7\u751f\u7269\u7684\u6280\u672f\u5b9e\u529b\u548c\u5de5\u4e1a\u5316\u6807\u51c6\u5c06\u786e\u4fddSRB5\u5728\u6700\u4f18\u6761\u4ef6\u4e0b\u5b9e\u73b0\u89c4\u6a21\u5316\u751f\u4ea7\u3002SRB5\u72ec\u7279\u7684\u751f\u7269\u5b66\u7279\u5f81\u6709\u671b\u6539\u53d8\u708e\u75c7\u6027\u80a0\u75c5\u4e43\u81f3\u9ad8\u4fb5\u88ad\u6027CCR9\u9633\u6027\u80bf\u7624\u7684\u6cbb\u7597\u683c\u5c40\uff0c\u8fd9\u4e00\u5408\u4f5c\u662f\u5411\u4e34\u5e8a\u9a8c\u8bc1\u8fc8\u51fa\u7684\u5173\u952e\u4e00\u6b65\u3002\u201d<\/p>\n<p><strong><b>\u9f0e\u5eb7\u751f\u7269\u603b\u88c1<\/b><\/strong><strong><b>\u9b4f\u5efa<\/b><\/strong><strong><b>\u4e2d<\/b><\/strong><strong><b>\uff08Jimmy Wei\uff09<\/b><\/strong><strong><b>\u535a\u58eb<\/b><\/strong>\u8868\u793a\uff1a\u201c\u6211\u4eec\u975e\u5e38\u9ad8\u5174\u80fd\u643a\u624bSunRock Biopharma\uff0c\u5171\u540c\u63a8\u52a8\u8fd9\u6b3e\u6781\u5177\u6f5c\u529b\u7684\u6297CCR9\u6297\u4f53\uff08SRB5\uff09\u5728\u708e\u75c7\u6027\u80a0\u75c5\u9886\u57df\u7684\u7814\u53d1\u3002IBD\u662f\u4e00\u79cd\u5168\u7403\u8303\u56f4\u5185\u5f71\u54cd\u6df1\u8fdc\u7684\u75be\u75c5\u3002\u672c\u6b21\u5408\u4f5c\u5f70\u663e\u4e86\u9f0e\u5eb7\u751f\u7269\u5728\u5168\u7403\u8d28\u91cf\u4f53\u7cfb\u4e0e\u751f\u7269\u836f\u5236\u9020\u7ecf\u9a8c\u65b9\u9762\u7684\u9886\u5148\u4f18\u52bf\uff0c\u6211\u4eec\u5c06\u7ee7\u7eed\u4ee5\u5353\u8d8a\u7684\u751f\u4ea7\u80fd\u529b\u548c\u8d28\u91cf\u6807\u51c6\uff0c\u52a0\u901f\u521b\u65b0\u7597\u6cd5\u7684\u4e34\u5e8a\u8f6c\u5316\uff0c\u52a9\u529bSunRock Biopharma\u5b9e\u73b0\u5176\u957f\u671f\u4f7f\u547d\u2014\u2014\u5f00\u53d1\u9488\u5bf9\u9ad8\u4fb5\u88ad\u6027\u80bf\u7624\u3001\u5177\u6709\u7d27\u8feb\u4e34\u5e8a\u9700\u6c42\u7684\u521b\u65b0\u6297\u4f53\u836f\u7269\u3002\u201d<\/p>\n<p><strong>\u5173\u4e8eSunRock Biopharma<\/strong><\/p>\n<p>SunRock Biopharma\u662f\u4e00\u5bb6\u603b\u90e8\u4f4d\u4e8e\u897f\u73ed\u7259\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u540c\u7c7b\u9996\u521b\uff08first-in-class\uff09\u4e0e\u540c\u7c7b\u6700\u4f18\uff08best-in-class\uff09\u7684\u6cbb\u7597\u6027\u6297\u4f53\u836f\u7269\uff0c\u9776\u5411\u80bf\u7624\u53ca\u514d\u75ab\u4ecb\u5bfc\u708e\u75c7\u6027\u75be\u75c5\u4e2d\u7684\u5173\u952e\u75c5\u7406\u901a\u8def\u3002\u516c\u53f8\u901a\u8fc7\u8bc6\u522b\u5728\u80bf\u7624\u8fdb\u5c55\u6216\u708e\u75c7\u4e2d\u5177\u6709\u6838\u5fc3\u4f5c\u7528\u7684\u9776\u70b9\uff0c\u7814\u53d1\u529f\u80fd\u589e\u5f3a\u7684\u5168\u4eba\u6e90\u6216\u4eba\u6e90\u5316\u6297\u4f53\uff0c\u5e76\u63a8\u52a8\u5176\u8fdb\u5165\u65e9\u671f\u4e34\u5e8a\u9636\u6bb5\uff0c\u4ee5\u8bb8\u53ef\u65b9\u5f0f\u4e0e\u5168\u7403\u5236\u836f\u516c\u53f8\u5408\u4f5c\u3002SunRock\u7684\u7ba1\u7ebf\u6db5\u76d6\u5355\u514b\u9686\u6297\u4f53\u3001\u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u53ca\u5176\u4ed6\u521b\u65b0\u6297\u4f53\u5f62\u5f0f\u3002\u516c\u53f8\u91c7\u7528\u5f00\u653e\u5f0f\u521b\u65b0\u6a21\u5f0f\uff0c\u4e0e\u6b27\u6d32\u3001\u7f8e\u56fd\u53ca\u4e9a\u6d32\u7684\u79d1\u7814\u673a\u6784\u548c\u884c\u4e1a\u4f19\u4f34\u5e7f\u6cdb\u5408\u4f5c\uff0c\u81f4\u529b\u4e8e\u5728\u53d6\u5f97\u6709\u529b\u7684\u4e34\u5e8a\u524d\u4e0e\u65e9\u671f\u4e34\u5e8a\u9a8c\u8bc1\u540e\uff0c\u901a\u8fc7\u6388\u6743\u5408\u4f5c\u5c06\u9879\u76ee\u8f6c\u5316\u4e3a\u5168\u7403\u521b\u65b0\u836f\u3002\u66f4\u591a\u4fe1\u606f\u8bf7\u8bbf\u95ee\uff1a<a href=\"http:\/\/www.sunrockbiopharma.com\"><u>www.sunrockbiopharma.com<\/u><\/a>\u3002<\/p>\n<p><strong>\u5173\u4e8e\u9f0e\u5eb7\u751f\u7269<\/strong><\/p>\n<p>\u9f0e\u5eb7\u751f\u7269\u662f\u4e00\u5bb6\u5168\u7403\u9886\u5148\u7684CDMO\u516c\u53f8\uff0c\u7387\u5148\u5f15\u8fdb\u4e86\u5168\u7403\u9996\u4e2a\u6a21\u5757\u5316\u751f\u7269\u5236\u836f\u5de5\u5382KUBio\u2122\uff0c\u8d4b\u80fd\u751f\u7269\u5236\u54c1\u4ece\u7ec6\u80de\u682a\u5f00\u53d1\u5230\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u5168\u8fc7\u7a0b\u3002\u6211\u4eec\u4f4d\u4e8e\u745e\u58eb\u5df4\u585e\u5c14\u7684\u6b27\u6d32\u521b\u65b0\u4e2d\u5fc3\u81f4\u529b\u4e8e\u63d0\u4f9b\u5feb\u6377\u7684\u5404\u7c7b\u6297\u4f53\u86cb\u767d\u77ac\u65f6\u8868\u8fbe\u751f\u4ea7\u670d\u52a1\uff0c\u4f4d\u4e8e\u4e0a\u6d77\u7684\u4e2d\u56fd\u521b\u65b0\u4e2d\u5fc3\u805a\u7126\u9ad8\u6548\u7684\u7ec6\u80de\u682a\u5f00\u53d1\u548c\u5148\u8fdb\u7684\u5de5\u827a\u5f00\u53d1\uff0c\u4e0e\u62e5\u6709\u591a\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u548c\u65b0\u836f\u4e0a\u5e02\u6210\u529f\u7ecf\u9a8c\u7684\u6b66\u6c49\u5236\u9020\u5de5\u5382\u76f8\u7ed3\u5408\uff0c\u9f0e\u5eb7\u751f\u7269\u6b63\u5728\u4e3a\u5168\u7403\u751f\u7269\u533b\u836f\u5ba2\u6237\u63d0\u4f9b\u4e00\u7ad9\u5f0f\u7684CMC\u89e3\u51b3\u65b9\u6848\u3002\u5728\u9f0e\u5eb7\u751f\u7269\uff0c\u6211\u4eec\u6709\u4e00\u4e2a\u5171\u540c\u7684\u76ee\u6807, 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